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札幌医学雑誌 第88巻

総    説

1. 疾患バイオマーカーの橋渡し研究
…………………………………………………………………………………………… 小海康夫 (1-6)

2. 鉄と肝疾患
……………………………………………………………………………… 加藤淳二,宮西浩嗣 (7-12)

3. 非侵襲的ヒト脳機能検索
…………………………………………………………………………………………… 長 峯 隆 (13-19)

原   著

1.Analysis of the anti-tumor mechanism of BRD4 inhibition in hepatocellular carcinoma
…………… Hajime SASAKI, Hiroshi KITAJIMA, Takeshi NIINUMA, Hideki WAKASUGI,
Kazuya ISHIGURO, Akira YOROZU, Gouta SUDO, Tomo HATAHIRA, Noriyuki AKUTU,
Eiichiro YAMAMOTO, Masahiro KAI, Shigeru SASAKI,Hiroshi NAKASE, Hiromu SUZUKI (21-35)

2.3 次元培養法による上眼瞼溝深化(deepening of the upper eyelid sulcus : DUES)
の分子病態に関する検討
………………………………………………………… 伊藤 格,日景史人,井田洋輔,大黒 浩(37-44)

3.白内障術後眼血流に眼軸長の及ぼす影響の検討
………………………………………………………… 井田洋輔,日景史人,伊藤 格,大黒 浩(45-51)

4.Patients living with chronic non-cancer pain receiving opioid therapy in Japan:
a grounded theory study
……………… Yukari SHINDO, Michiko AOYANAGI, Soshi IWASAKI, Michiaki YAMAKAGE (53-64)

5.Dexmedetomidine attenuates surgery-induced cognitive deficit and hippocampal Mapt
expression in aged mice
……………………………… Shunsuke TACHIBANA, Tomo HAYASE, Michiaki YAMAKAGE (65-76)

研究論文紹介

1.Self-renewal capability of hepatocytic parental progenitor cells derived
from adult rat liver is maintained long term when cultured on laminin 111 in
serum-free medium.    Hepatol Commun. 2019; 4(1): 21-37.
…………………………………………………………………………Norihisa ICHINOHE et al. (78-79)
2.Immunohistological analysis of pancreatic carcinoma after vaccination with
survivin 2B peptide: analysis of an autopsy series.  Cancer Sci. 2019; 110(8): 2378-2385
…………………………………………………………………………… Teruhumi KUBO et al. (80-81)
3.p16INK4A-expressing mesenchymal stromal cells restore the senescence–
clearance– regeneration sequence that is impaired in chronic muscle inflammation.
EBioMedicine 2019; 44: 86-97
……………………………………………………………………………Takako CHIKENJI et al. (82-83)

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