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札幌医学雑誌 第87巻

総    説

1.蛋白質脱アセチル化酵素SIRT1の機能と病態への関与
……………………………………………………………………………………… 堀尾嘉幸      (1-8)
2.脳神経内科疾患研究の歩み
……………………………………………………………………………………… 下濱 俊     (9-23)

原    著

1.Cardiac troponin I and perioperative factors in pediatric open heart surgery
……………… Tsutomu WADA, Masato YOKOZAWA, Motoki TAKAMURO, Dai ARAKI,
…………………………………Norihiko EBUOKA, Junichi OHBA, Tsuyoshi TACHIBANA,
………………………………………………………… Mitsuru MORI, Hiroyuki TSUTSUMI    (25-33)

2.Denosumab prevents bone loss in newly diagnosed malignant lymphoma patients
undergoing corticosteroid-containing chemotherapy: a prospective, non-randomized study
…………………Ayumi TATEKOSHI, Tsutomu SATO, Satoshi IYAMA, Kohichi TAKADA,
……………………Kazuyuki MURASE, Masahiro YOSHIDA, Soushi IBATA,
……………………SHIMOTO,Yusuke KAMIHARA, Hiroto HORIGUCHI, Koji MIYANISHI,
…………………………………………………………… Masayoshi KOBUNE, Junji KATO    (35-47)

3.Low-dose interleukin-2 induces BCL2 expression and resistance to apoptosis in CD4
regulatory T Cells
…………… Teppei MATSUNO, Kazuyuki MURASE, Kohichi TAKADA, Yutaka KAWANO,
……………   Masahiro HIRAKAWA, Koji MIYANISHI, Masayoshi KOBUNE, Junji KATO   (49-61)

4.Parental rearing attitudes in childhood is associated with adult sleep disturbances
independently from depression and life events: a cross-sectional survey in Japan
……………………………………………. Motoki AMAI, Masanori NOJIMA, Toshio SATO,
……………………………………………………………  Yukari UDAGAWA, Mitsuru MORI   (63-74)

5.The roles of metformin and pravastatin on placental endoplasmic reticulum stress and
placental growth factor in human villous-Like trophoblastic BeWo cells
………………………………… Masahiro SUZUKI, Masahito MIZUUCHI, Tsuyoshi BABA,
……………………………………… …Yoshihiko INO, Shinichi ISHIOKA, Tsuyoshi SAITO   (75-84)

6.Is the number of covered intercostal arteries a predictor of postoperative spinal
cord ischemia after thoracic endovascularaortic repair?
……………………. Yosuke KURODA, Toshiro ITO, Hiroki UCHIYAMA, Naomi YASUDA,
……………………………………………………Toshitaka WATANABE, Junji NAKAZAWA,
……………………………………………………Ryo HARADA, Nobuyoshi KAWAHARADA    (85-92)

研究論文紹介

1.特発性後腹膜線維症に対する治療成績の検討 -IgG4 関連疾患の積極的診断を考慮
した診断・治療プロトコールの検証. 泌尿器科紀要. 2017; 63: 449-454.
…………………………………………………………………………………  伊與木貴也 et al.   (94-95)

2.Hepatocytic parental progenitor cells of rat small hepatocytes maintain
self-renewal capability after long-term culture. Sci Rep. 2017 Apl 11; 7: 46177
……………………………………………………………………………… Masayuki ISHII et al.  (96-97)

3.mRNA-binding protein tristetraprolin is essential for cardiac response to
iron deficiency by regulating mitochondrial function.
Proc Natl Acad Sci U S A. 2018 Jul 3; 115(27): E6291-E6300
………………………………………………………………………………. Tatsuya SATO et al.   (98-99)

4.Antagonists to TRPV1, ASICs and P2X have a potential role to prevent
the triggering of regional bone metabolic disorder and pain-like behavior in
tail-suspended mice.  Bone. 2018 May;110:284-294. doi: 10.1016/j.bone.2018.02.006
…………………………………………………………………………. Megumi HANAKA et al.  (100-101)

5.The Antigen ASB4 on Cancer Stem Cells Serves as a Target for CTL Immunotherapy
of Colorectal Cancer. Cancer Immunol Res. 2018 Jan 25; doi: 10.1158/2326-6066.CIR-17-0518.
……………………………………………………………………………. Sho MIYAMOTO et al.  (102-103)

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札幌医学雑誌 第84巻

総    説

1.札幌医科大学における 38 年間の研究について

…………………………………………………………………………………………… 山下利春   (1-5)

2.口腔癌の外科治療:国際共同研究の結果と比較して治療結果を検証する

………………………………………… 平塚博義,宮崎晃亘,出張裕也,荻   和弘,三木善樹,

………………………………………… 小林淳一,上田  愛,五十嵐友彦,島西真琴,仲盛健治,

………………………………………… 宮川 明,関口 隆,井出 隆           (7-11)

3.間質性肺炎とサーファクタント蛋白質

…………………………………………………………………………………………… 高橋弘毅(13-17)

原    著

1.Net-step exercise and depressive symptoms among the community-dwelling elderly in Japan

………………Satoko SHOWA, Kazutoshi KITAZAWA, Miki TAKEUCHI, Mitsuru MORI   (19-26)

2.   Factors influencing attitudes toward end-of-life care by  care  workers  at  special  nursing

homes for the elderly: A cross-sectional study in Japan

………………………………………  Michiyo  YAMAMOTO,  Hirofumi  OHNISHI,  Asae  OURA,

…………………Takeshi  YAMAMOTO,  Hisako  IZUMI,  Miwa SUZUMURA,Mitsuru MORI      (27-33)

研究論文紹介

1.Increased duodenal iron absorption through up-regulation of  divalent  metal  transporter

1 from enhancement of iron regulatory protein 1 activity in patients with nonalcoholic

steatohepatitis. Hepatology. 2015 Sep; 62(3): 751-761

………………………………………………………………………… Toshifumi HOKI et al. (36-37)

2.Evaluation of language function under awake.

Neurol Med Chir (Tokyo). 2015; 55(5): 367-373

………………………………………………………… Aya KANNO and Nobuhiro MIKUNI (38-39)

3.Suppression of bone marrow-derived microglia in the amygdala improves anxiety-like behavior

induced by chronic partial sciatic nerve ligation in mice. PAIN 2014; 155(9): 1762-1772

………………………………………………………………………… Atsushi SAWADA et al. (40-41)

4.Intravenous preload of mesenchymal stem cells rescues erectile function in a rat model of

cavernous nerve injury. J Sex Med 2015; 12(8): 1713-1721

………………………………………………………………………… Akio TAKAYANAGI et al. (42-43)

5.Downregulation of miR122 by grainyhead like-2 restricts the hepatocytic differentiation potential

of adult liver progenitor cells. Development 2014; 141(23): 4448-4456

………………………………………………………………………… Naoki TANIMIZU et al. (44-45)

編集後記

札幌医学雑誌 第85巻

総    説

1.高血圧, メタボリックシンドロームの疫学・基礎・臨床研究による包括的研究

……………………………………………………………………………………………..島本和明 (1-5)

2.研究経営論: 過去・現在・未来の公衆衛生学の研究

…………………………………………………………………………………………….. 森   満 (7-11)

3.ホメオスタシスを維持するタイト結合とヒト疾患

……………………………………………………………………………………………..澤田典均(13-20)

4. ウイルス性炎症における上気道粘膜の役割と免疫応答

……………………………………………………………………………………………..氷見徹夫(21-27)

原    著

1.中年期女性の尿失禁のリスク要因の検討

……………………………………………………………………………………….. 原井美佳, 森  満(29-32)

2.BK channels in human periodontal ligament fibroblasts

………… 白鳥香理, 小林武志, 深尾充宏, 出張裕也, 宮崎晃亘, 平塚博義, 當瀬規嗣    (33-38)

3.    Factors Influencing Attitudes toward End-of-life Care by Care Workers at Special Nursing

Homes for the Elderly: A Longitudinal Study in Japan

…………….. Michiyo YAMAMOTO, Asae OURA, Takeshi YAMAMOTO, Hisako IZUMI,

・・・・・・Miwa SUZUMURA, Hirofumi OHNISHI, Mitsuru MORI ・・・ (39-45)

 

活 動 報 告

1 性暴力被害者支援センター北海道(SACRACH)

…………………… 堀本江美, 平山恵美, 須見よし乃, 宮崎みち子, 渡邊由加利          (49-52)

研究論文紹介

 

1.Brother of the regulator of the imprinted site (BORIS) variant subfamily 6 is

involved in cervical cancer stemness and can be a target of immunotherapy.

Oncotarget 2016; 8(7): 11223-11237

……………………………………………………………………………………….. Takuya ASANO  et al.(54-55)

2.The influence of anesthetic depth on motor evoked potential response during awake craniotomy.

J Neurosurg 2016; Mar 4:1-6.

……………………………………………………………………………………….. Shunya OHTAKI  et al.(56-57)

3.Low-frequency IL23R coding variant associated with Crohn’s disease susceptibility in Japanese

subjects identified by personal genomics analysis. PLoS One 2015; 10: e0137801

……………………………………………………………………………………….. Kei ONODERA  et al.(58-59)

4.Cancer-Associated Oxidase ERO1-α Regulates the Expression of MHC Class I Molecule via

Oxidative Folding.  J Immunol 2015; 194(10): 4988-4996

…………………………………………………………………………………… Kazuharu KUKITA  et al. (60-61)

5.Microenvironmental stresses induce HLA-E/Qa-1 surface expressionand thereby reduce CD8(+)

T-cell recognition of stressed cells. Eur J Immunol 2016; 46: 929-940

…………………………………………………………………………………. Takanori SASAKI et al. (62-63)

6. Severity of myasthenia gravis influences the relationship between train-of-four ratio and twitch

tension, and run-down of rat endplate potentials.  Anesthesiology 2016; 124(2): 369-377

………………………………………………………………………………. Kazunobu TAKAHASHI et al.(64-65)

7. Heat shock protein 90α is a potential serological biomarker of acute rejection after renal

transplantation. PLoS One 2016; 11(9): e0162942.

……………………………………………………………………………………. Takeshi MAEHANA et al.(66-67)

編集後記

札幌医学雑誌 第86巻

総    説

  1. ウイルスとこども達

………………………………………………….. 堤  裕幸,要藤裕孝,堀    司,津川  毅,山本雅樹   (1-8)

  1. 地域医療総合医学講座の研究

………………………………………………………………..………..……………………….. 山本和利 (9-16)

原    著

  1. 無作為抽出された道内二市住民,40歳代から70歳代の抑うつ所見と
    口渇及び服薬との関連

………………………………………………………………………………………….. 鈴木恵三,森    満(17-23)

  1. Factors related to depression among childcare worker; Cross-sectional study
    in Hokkaido, Japan

…………………Asae OURA, Miwa SUZUMURA, Michiyo YAMAMOTO, Hiroko YAKO-SUKETOMO,
………………………………Kayoko KATAYAMA, Asako TOKIZAWA, Tomoyo SATO, Mitsuru MORI (25-32)

  1. 開放隅角緑内障患者における視野障害進行因子の検討

……………………………..………………. 近藤みどり,梅田和志,稲富周一郎,大黒幾代,大黒 浩(33-43)

     4.Early expression of serum CCL8 closely correlates to non-relapse mortality after allogeneic
           hematopoietic stem cell transplantation
………………….…Masaki YAMAMOTO, Tsukasa HORI, Naoki HATAKEYAMA, Keita IGARASHI,
……………….……Natsuko INAZAWA, Nobuhiro SUZUKI, Norio TAKEI, Yoichi M. ITO,
…………………….……Kimikazu MATSUMOTO, Koji KATO, Hiroyuki TSUTSUMI, Yasuo KOKAI   (45-51)

  1. Comparisons of kinematics during stair motion in total  knee  arthroplasty:
    Single-radius versusJ-curved designs

………………….Yuichiro KII, Tetsuya TOMITA, Takaharu YAMAZAKI, Hideki YOSHIKAWA,
………………………….Hideki YOSHIKAWA,Toshihiko YAMASHITA, Kazuomi SUGAMOTO
……(53-61)

     6. SIRT1 negatively regulates the expression of Prl2C3, a senescence-associated protein
………………………Kohei HORIMOTO, Risa KUNIMOTO, Risa HASHIMOTO, Naohiro UEDA,
……………….……Ryusuke HOSODA, Atsushi KUNO, Toshiharu YAMASHITA, Yoshiyuki HORIO (63-71)

  1. Acupuncture’s evidences: even slight stimuli could alter body functions, suggesting a “resetting” effect

…………………………………….………………………… Shougo MIZOGUCHI, Haruyuki TATSUMI (73-83)

  1. Are ADC histogram metrics repeatable?

………………………………… Koichi ONODERA, Naoya YAMA, Maki ONODERA, Naomi KOYAMA,
………………………..…… Yoshifusa KYUNA, Mitsuhiro NAKANISHI, Masamitsu HATAKENAKA (85-93)

研究論文紹介

  1. Toll-like receptor 7 is overexpressed in the bladder of Hunner type interstitial
    cystitis and its activation in the mouse bladder can induce cystitis and bladder pain.
    Pain. 2017; 158(8):1538-1545

…………………………………………………………………….………….……… Koji ICHIHARA et al.(96-97)

  1. Transplantation of Thy1+ cells accelerates liver regeneration by enhancing
    the growth of small hepatocyte-like progenitor cells via IL17RB Signaling.
    Stem Cells. 2017; 35: 920-931

……………………………………………………………….…………….…… Norihisa ICHINOHE et al.(98-99)

  1. MicroRNA-196b is an independent prognostic biomarker in  patients  with  pancreatic.

Carcinogenesis. 2017; 38(4): 425-431

………………………………………………………………….………….……… Shinichi KANNO et al.(100-101)

  1. The bicellular tensile force sorts the localization  of  LSRs  in  bicellular  and  tricellular junctions.

Ann N Y Acad Sci. 2017; 1397(1): 185-194

………………………………………………………………….…………….……Takayuki KOHNO et al.(102-103)

  1. Prolyl isomerase Pin1 promotes survival in EGFR-mutant lung
    adenocarcinoma cells with an epithelial-mesenchymal transition phenotype.
    Lab Invest. 2016; 96(4): 391-398

………………………………………………………………….……….……………… Yuji SAKUMA et al.(104-105)

  1. Chronic treatment with an erythropoietin receptor ligand prevents chronic kidney
    disease–induced enlargement of myocardial infarct size. Hypertension. 2016; 68(3): 697-706

………………………………………………………………….……….…………Keitaro NISHIZAWA et al.(106-107)

  1. Reduction of HbA1c levels by fucoxanthin-enriched akamoku oil possibly
    involves the thrifty allele of uncoupling protein 1 (UCP1): a randomised
    controlled trial in normal-weight and obese Japanese adults.
    J Nutr Sci. 2017 Feb 14;6:e5.

…………………………………………………………………….…….……………… Nana MIKAMI et al.(108-109)

  1. Identification of a novel human memory T cell population with the characteristics
    of stem-like chemo-resistance.   OncoImmunology. 2016; 5:e1165376.

…………………………………………………………………….…….……………… Kenji MURATA et al. (110-111)

編集後記

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